Para aumentar a libido sexual .... Yohimbe.

A Yohimbe  

Doses: 100mg diárias ( Não tem função anabólica - somente aumento de libido )

            Usado durante séculos na África Ocidental, a casca da árvore yohimbe era usada como um chá para aumentar o  
    desejo sexual e a virilidade. Por mais de 50 anos, antes do advento do Viagra, Cialis e Levitra, um extrato da casca da
    árvore yohimbe, com o seu princípio ativo chamado ioimbina (yoimbine), era usado nos Estados Unidos para tratar
    problemas sexuais em mulheres e homens. Também usado como afrodisíaco, o Ioimbe tem a capacidade de quando
    ingerido aumentar a circulação sanguínea nos órgãos genitais de mulheres e homens.
            Alguns experimentos em humanos mostraram que a Ioimbina (yohimbine) provê benefícios se a disfunção erétil
    não for resultado de nenhuma causa orgânica. Quer dizer, a Ioimbina é eficaz se a diminuição da libido for resultado de
    tensão, ansiedade ou do avanço da idade (envelhecimento), e não devido a qualquer enfermidade, incluindo
    hipogonadismo e condições psiquiátricas.
           O mais recente estudo alemão publicado em 1997 mostrou que 71% de 83 homens diagnosticados com disfunção
    erétil responderam favoravelmente ao tratamento com a iohimbina, dentro de um período de 8 semanas. O mais
    importante que deveria ser observado é que o extrato de yohimbe não requer testosterona como base para se aumentar
    a libido.

A Unique formula
Dr. Sahelian and his research staff tested numerous doses and extracts of dozens of herbs from a number or raw material suppliers to determine the ideal dosage and combination for optimal aphrodisiac properties with the fewest side effects. Passion Rx supports and enhances healthy:

•      Libido and sexual thoughts
•      Erectile function and genital sensation
•      Orgasms and climaxes
•      Energy and stamina 

The potent herbal extracts in Passion Rx include ashwagandha, catuaba, cnidium, herba cistanches, Horny Goat Weed, Maca, Muira puama, Passion flower, Tongkat Ali and LJ100, Tribulus and Yohimbe. You will also find Passion Rx without yohimbe.

Natrol Yohimbe Bark supplement 500 mg each pill
Whole Herb Yohimbe Powder Dietary Supplement, powdered bark 500 mg
Not an extract


 

Directions: Take half a yohimbe capsule two to three hours before intimacy. If you are sensitive to herbs, take less than half. This herbal product is not recommended for anyone with heart problems or who has heart irregularities. Some people with clinical impotence or erectile dysfunction may have underlying heart disease. Be cautious using herbs or drugs for sexual enhancement until a thorough medical evaluation has been done.

Yohimbe side effects and cautions, risks and danger
Yohimbe should be used cautiously by anyone with a medical condition, particularly those with unstable hypertension, heart disease, diabetes, or those taking medicines, particularly tranquilizers, antidepressants, sedatives, antihistamines, amphetamines and other stimulants, including caffeine and herbal stimulants such as ginseng. Some of the side effects of high dose yohimbe include anxiety, changes in blood pressure, heart rate increase, palpitations, dizziness, headache, visual disturbances, nausea or abdominal cramps, increased body temperature and sweating. I do not recommend this herb to anyone over the age of 65. Since high doses may cause confusion and disorientation, it should not be taken while operating machinery, driving, or performing hazardous activities. In most people it raises blood pressure and it is dosage dependent.
   As with many herbs or medicines, the right dose works well but too high a dose causes side effects. If you have moderate to severe hypertension, then you should avoid yohimbe. However, if you have mild hypertension, then small amounts, that is, less than 150 mg, should be fine, especially with the consent of your doctor. The blood pressure effects don't last all day, only a few hours. The first thing you may notice after an hour or two is sweating under the arms. On higher doses you will notice a higher body temperature, an even higher doses of yohimbe lead to slightly blurred vision, mild anxiety, and a sense of not feeling well. Very high doses lead to heart palpitations. Fortunately, most of these yohimbe side effects only last an hour or two.

Do not use this herbal product if you have heart disease (including irregular rhythm), kidney, thyroid or liver disease, a seizure disorder or stroke. Do not take it with any antidepressant medications or MAO inhibitors, or with foods containing high amounts of tyramine (such as cheese or red wine) or with decongestants, diet aids, products containing phenylpropanolamine, hormones such as DHEA or pregnenolone, or supplements that have a stimulating effects, such as sexual enhancement herbs, SAM-e, tyrosine, etc. Consult with your doctor before use if you have any health problems or are taking any medications. Discontinue use and consult your doctor if you experience high blood pressure, heart palpitations or rapid heart beat, dizziness, headache, rash, tremors, depression or hallucinations. Other adverse reactions may include nervousness, anxiety, mood changes, insomnia, nausea, vomiting, urinary retention, dilation of pupils, or skin flushing. The adverse effects are dose dependent.

Yohimbine versus yohimbe bark
Yohimbine is a drug approved by the FDA for the treatment of erectile dysfunction. Almost all clinical studies have been conducted with it rather than yohimbe bark powder or extracts. For more than 80 years it has been used as a treatment for male and female sexual difficulties. In my opinion, yohimbe bark works quite well. I have tried yohimbine, and I actually prefer the yohimbe bark supplement.

Yohimbine has been evaluated in the management of erectile disorder by means of many placebo-controlled trials. It does appear to have a therapeutic benefit. In contract, yohimbe has not been studied much. Here's one summary of a study:
   A 1977 German double-blind, placebo-controlled clinical trial of yohimbine hydrochloride included 86 patients with erectile dysfunction and without clearly detectable organic or psychologic causes. Yohimbine was administered orally in a dosage of 30 mg a day (two 5 mg tablets three times daily) for eight weeks. Patients were seen for follow-up after four weeks' treatment, and for a final visit after eight weeks. Efficacy evaluation was based on both subjective and objective criteria. Subjective criteria included improvement in sexual desire, sexual satisfaction, frequency of sexual contacts, and quality of erection (penile rigidity) during sexual contact/intercourse. Objective criteria of outcome were based on improvement in penile rigidity determined by use of polysomnography in the sleep laboratory. Overall Yohimbine was found significantly more effective than placebo in terms of response rate: 71 vs 45%. Yohimbine was well-tolerated: Only 7% of patients rated tolerability fair or poor, and most adverse experiences were mild. There was no serious adverse event.
Weight loss
Some companies promote this plant for weight loss. I have not found this herb effective for the purposes of losing weight. The adverse effects are too annoying for it to be effective for this purpose.
Would a woman benefit?
A study conducted at the University of Texas at Austin, Texas examined the effects of arginine combined with yohimbine on sexual arousal in postmenopausal women with Female Sexual Arousal Disorder. Twenty-four women participated in three treatment sessions in which self-report and vaginal sexual responses to erotic stimuli were measured following treatment with either L-arginine (6 g) plus yohimbine (6 mg), yohimbine alone (6 mg), or placebo, using a randomized, double-blind, three-way cross-over design. Sexual responses were measured at approximately 60 minutes postdrug administration. The combined oral administration of L-arginine and yohimbine substantially increased vaginal pulse amplitude responses to the erotic film at 60 min postdrug administration compared with placebo. The vaginal response was measured with an instrument called a vaginal photoplethysmograph.
   Even though yohimbe was not tested, it would make sense that it would also have similar activity.
I just bought the yohimbe bark yesterday but I was wondering if I suggest it to my wife would this get her horny? She doesn't like medicine or vitamins.
    Many women notice sexual benefits from the use of this herb, but it is best to use low dosages, a portion of a tablet or capsule, since adverse effects are quite common in a woman on higher dosages. This supplement can be used with coke or a soft drink but it is best not to combine it with alcohol.

Mechanism of action, how it works
Yohimbine acts through the nervous system to increase blood flow to the genital region. Although many pharmacological properties have been described, at the plasma concentration attained at recommended dosages in humans the predominant activity is antagonism of alpha 2-adrenoceptors. Yohimbine is a specific extract from yohimbe bark. It is not clear whether the other alkaloids in the bark also have a pro-sexual effect.

Availability of supplements, how they are sold, dosage
Yohimbe bark is sold widely in different dosages and extract potencies including 4%, 6%, 8%, and 10% alkaloids. It is difficult to give precise dosage recommendations for extracts since sometimes manufacturers and formulas are not consistent in their content or extract potencies of yohimbe. In one study, of twenty commercial aphrodisiac preparations were analyzed and the amount of yohimbine measured and expressed as the maximal dose per day suggested on product labels ranged from 1.3 to 23.1 mg.

Timing and frequency of use
Yohimbe may be used either daily or before planned activity. In my opinion, since it works quite quickly, it makes sense that it be taken as needed one to three hours before planned sexual activity rather than taken daily. The effects last several hours. I don't recommend you take it close to bedtime since it can have a stimulant and alertness causing effect for several hours. I don't recommend you mix yohimbe with alcohol or stimulant drugs, including high doses of caffeine.
Yohimbe research studies
Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats.
Methods Find Exp Clin Pharmacol. 2003.
In vivo studies with yohimbe in Sprague Dawley rats demonstrated a dose-dependent increase in mean blood pressure and an increase in medullary blood flow (MBF). Both the pressor action and renal medullary vasodilation of yohimbe were blocked by endothelinA (ETA) receptor antagonist BMS182874 and endothelinB (ETB) receptor antagonist BQ788 in combination. L-Nomega-nitro-l-arginine methyl ester (L-NAME; 10 mg/kg) also inhibited the increase in MBF induced by yohimbe. In vitro studies in isolated perfused kidney and in pressurized renal microvessels confirmed the dose-dependent vasoconstrictor action of this extract. ETA receptor antagonist BQ610 and ETB receptor antagonist BQ788 separately and significantly attenuated the renal vasoconstrictor actions of the yohimbe extract. These preliminary observations indicate that, in addition to the alpha-adrenergic antagonist actions that characterize yohimbine, yohimbe possesses endothelin-like actions and affects nitric oxide (NO) production in renal circulation. These findings suggest a strong possibility of post-receptor cross-talk between alpha2-adrenoceptors and endothelin, as well as a direct effect of alpha2-adrenoceptors on renal NO production.